{"id":23,"date":"2026-09-02T11:31:21","date_gmt":"2026-09-02T03:31:21","guid":{"rendered":"https:\/\/hmnprc.tcu.edu.tw\/?page_id=23"},"modified":"2026-09-16T18:16:03","modified_gmt":"2026-09-16T10:16:03","slug":"%e7%a0%94%e7%a9%b6%e5%a0%b1%e5%91%8a","status":"publish","type":"page","link":"https:\/\/hmnprc.tcu.edu.tw\/?page_id=23","title":{"rendered":"Publications"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Selected peer-reviewed publications by members of the Center for Herbal Medicine and Natural Products Research. Entries are arranged in reverse chronological order. Journal metrics use the 2025 Journal Citation Reports released in 2026; \u201cTop %\u201d is calculated from the displayed category rank and rounded to the nearest whole percent.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2026<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Comparing the Behavioral Impacts of Heavy Metals and Rare Earth Elements on Black Soldier Fly (<em>Hermetia illucens<\/em>) Larvae<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Muhammad Baqir Khan, Minh-Quan Tran, Petrus Siregar, Szu-Chieh Wang, <strong>Ming-Der Lin*<\/strong>, and Chung-Der Hsiao*.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Toxics<\/em>. August 2026; 14(8), 729. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.3390\/toxics14080729\">10.3390\/toxics14080729<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 4.9 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 21\/106, Toxicology &nbsp; | &nbsp; <strong>Top 20%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">High-Throughput Pesticide Toxicity Assessment in Black Soldier Fly (<em>Hermetia illucens<\/em>) by Behavioral Phenomics<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Petrus Siregar, Gilbert Audira, Kevin Adi Kurnia, Szu-Chieh Wang, Marri Jmelou M. Roldan, Kristine Mae H. Bonalos, Ross D. Vasquez, <strong>Ming-Der Lin*<\/strong>, and Chung-Der Hsiao*.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Pesticide Biochemistry and Physiology<\/em>. August 2026; 222, 107244. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1016\/j.pestbp.2026.107244\">10.1016\/j.pestbp.2026.107244<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 4.0 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 3\/110, Entomology &nbsp; | &nbsp; <strong>Top 3%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Receptor Pharmacology, Clinical Evidence, and Translational Challenges of Phenylpropanoid Phytoestrogens in Estrogen-Deficiency Osteoporosis<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Yi-Tzu Lin\u2020<\/strong>, <strong>Chi-Ying Li\u2020<\/strong>, Wen-Ying Lin, Cheng-Huan Peng*, and <strong>Ming-Der Lin*<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Tzu Chi Medical Journal<\/em>. Accepted, August 2026. <strong>DOI:<\/strong> Not yet assigned.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 2.4 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 94\/336, Medicine, General &amp; Internal &nbsp; | &nbsp; <strong>Top 28%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">A Simple Oral STZ\/Alloxan-Induced Diabetic Zebrafish Model for Chronic Wound Healing and Therapeutic Assessment<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Kong-Han Ser, Minh-Quan Tran, Szu-Chieh Wang, <strong>Ming-Der Lin*<\/strong>, and Chung-Der Hsiao*.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Biomedicine &amp; Pharmacotherapy<\/em>. July 2026; 200, 119352. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1016\/j.biopha.2026.119352\">10.1016\/j.biopha.2026.119352<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 7.5 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 19\/352, Pharmacology &amp; Pharmacy &nbsp; | &nbsp; <strong>Top 5%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Therapeutic Advances in Alzheimer\u2019s Disease: Current Strategies and Future Possibilities<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Peeraporn Varinthra<\/strong>, Ayooluwa Gabriel Ibiayo, <strong>Chin-Hung Liu<\/strong>, Narawut Pakaprot, Ismat Noor Paromi, Thi-Thuy-Nhan Do, Mubashir Raza, and <strong>Ingrid Y. Liu*<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Tzu Chi Medical Journal<\/em>. 2026; 38(3), 263\u2013274. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.4103\/tcmj.tcmj-d-25-00175\">10.4103\/tcmj.tcmj-d-25-00175<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 2.4 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 94\/336, Medicine, General &amp; Internal &nbsp; | &nbsp; <strong>Top 28%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Engineering Plants for the Phytoremediation of Soils Contaminated with Chlorinated Dioxins<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Wen-Ling Wei, Althea Yi-Shan Li, Chih-Ming Kao, Anren Hu, Hung-Yu Shu, Chiu-Ping Cheng, Chia-Chin Liu, Shinn Zong Lin, Tsung-Jung Ho, <strong>Ming-Lun Chou*<\/strong>, and Hao-Ping Chen*.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Environmental Technology &amp; Innovation<\/em>. June 2026; 42, 104964. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1016\/j.eti.2026.104964\">10.1016\/j.eti.2026.104964<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 7.1 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 16\/177, Biotechnology &amp; Applied Microbiology &nbsp; | &nbsp; <strong>Top 9%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">TiO<sub>2<\/sub> Nanoparticles Trigger Gut-to-Gill Bacterial Translocation and Dysbiosis in Zebrafish<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Chi-Cheng Li, Der-Shan Sun, Te-Sheng Lien, Guan-Ling Lin, Ching-Feng Cheng, Kuo-Wang Tsai, Wen-Sheng Wu, Chi-Tan Hu, <strong>Ming-Der Lin<\/strong>, Wen-Ying Lin, Chin-Hao Yang, Je-Wen Liou, and Hsin-Hou Chang*.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>International Journal of Molecular Sciences<\/em>. June 2026; 27(11), 5036. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.3390\/ijms27115036\">10.3390\/ijms27115036<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 5.6 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 72\/319, Biochemistry &amp; Molecular Biology &nbsp; | &nbsp; <strong>Top 23%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Tumor Necrosis Factor-Alpha-Mediated Inflammatory Bone Loss: Pathogenic Mechanisms and Therapeutic Potential of Its Inhibitors<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Wen-Ying Lin, Yu-Jen Pan, Kuang-Ting Yeh, Kuei-Ying Su, Kameshwara Kumar Dharini, Ing-Ho Chen, Wen-Tien Wu, <strong>Ming-Der Lin*<\/strong>, and Cheng-Huan Peng*.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Tzu Chi Medical Journal<\/em>. April 2026; 38(2), 125\u2013136. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.4103\/tcmj.TCMJ-D-25-00128\">10.4103\/tcmj.TCMJ-D-25-00128<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 2.4 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 94\/336, Medicine, General &amp; Internal &nbsp; | &nbsp; <strong>Top 28%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Zebrafish PRL-3 Regulates Yolk Syncytial Layer Integrity and Actomyosin Contractility During Epiboly<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ting-Fang Wang, Kai-Wen Cheng, Yau-Hung Chen*, and <strong>Ming-Der Lin*<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>International Journal of Molecular Sciences<\/em>. March 2026; 27(5), 2339. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.3390\/ijms27052339\">10.3390\/ijms27052339<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 5.6 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 72\/319, Biochemistry &amp; Molecular Biology &nbsp; | &nbsp; <strong>Top 23%<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2025<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Developmental Expression of Ap-Vas Proteins in Aphids and Flies Reveals Their Evolutionary Roles in Insects<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Gee-Way Lin, Szu-Chieh Wang, Charles E. Cook, <strong>Ming-Der Lin*<\/strong>, and Chun-che Chang*.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Insect Molecular Biology<\/em>. November 2025. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1111\/imb.70020\">10.1111\/imb.70020<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 2.3 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 22\/110, Entomology &nbsp; | &nbsp; <strong>Top 20%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Activation of GABA Transmission by Clonazepam Reverses the Autistic-Like Phenotypes of the Cav3.2 Knockout Mice<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Shao-Feng Liang, Ming Yang, Hsien-Ting Huang, Raymond Y. Lo, Supin Chompoopong, Chien-Chang Chen, and <strong>Ingrid Y. Liu*<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Neurotherapeutics<\/em>. October 2025; 22(6), e00761. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1016\/j.neurot.2025.e00761\">10.1016\/j.neurot.2025.e00761<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 7.4 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 21\/296, Clinical Neurology &nbsp; | &nbsp; <strong>Top 7%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Combination Astragaloside IV and Artesunate Preserves Blood\u2013Brain Barrier Integrity by Modulating Astrocytes and Tight Junction Proteins in <em>Plasmodium yoelii<\/em> Infection<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Phornyupa Sanguanwong, Ladawan Khowawisetsut, Lanaprai Kwathai, <strong>Peeraporn Varinthra<\/strong>, Chairat Turbpaiboon, Panapat Uawithya, Prasert Sobhon, <strong>Ingrid Y. Liu<\/strong>, and Supin Chompoopong.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>International Journal for Parasitology: Drugs and Drug Resistance<\/em>. August 2025; 28, 100598. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1016\/j.ijpddr.2025.100598\">10.1016\/j.ijpddr.2025.100598<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 3.3 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 11\/47, Parasitology &nbsp; | &nbsp; <strong>Top 23%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Coniferaldehyde Reverses 3-Nitropropionic Acid-Induced Huntington\u2019s Disease Pathologies via PKM2 Restoration and JAK2\/STAT3 Inhibition<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Ayooluwa Gabriel Ibiayo, <strong>Peeraporn Varinthra<\/strong>, Mukundan Nagarajan, and <strong>Ingrid Y. Liu*<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Molecular Medicine<\/em>. July 2025; 31(1), 271. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1186\/s10020-025-01308-0\">10.1186\/s10020-025-01308-0<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 8.3 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 38\/328, Biochemistry &amp; Molecular Biology &nbsp; | &nbsp; <strong>Top 12%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">GABAergic Signaling Underlying REM Sleep Deprivation-Induced Spatial Working Memory Deficits<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Peeraporn Varinthra<\/strong>, Shu-Ching Shih, and <strong>Ingrid Y. Liu*<\/strong>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Brain and Behavior<\/em>. June 2025; 15(6), e70607. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1002\/brb3.70607\">10.1002\/brb3.70607<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 2.8 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 18\/57, Behavioral Sciences &nbsp; | &nbsp; <strong>Top 32%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Automated Zebrafish Spine Scoring System Based on Instance Segmentation<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">Wen-Hsin Chen, Tien-Ying Kuo*, Yu-Jen Wei, Cheng-Jung Ho, <strong>Ming-Der Lin<\/strong>, Huan Chen, and Wen-Ying Lin.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>IEEE Access<\/em>. January 2025; 13, 18814\u201318826. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.1109\/ACCESS.2025.3532680\">10.1109\/ACCESS.2025.3532680<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 3.4 &nbsp; | &nbsp; <strong>Category Rank:<\/strong> 87\/250, Computer Science, Information Systems &nbsp; | &nbsp; <strong>Top 35%<\/strong><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Pro-Angiogenic Effects of Guo Min Decoction in a Zebrafish Model<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Ping-Hsun Lu<\/strong>, Sheng-Fen Tung, Chi-Chung Wen, Ching-Yuan Huang, Jhih-Wei Huang, Chih-Hsin Chen, and Yau-Hung Chen*.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Tzu Chi Medical Journal<\/em>. January\u2013March 2025; 37(1), 58\u201364. <strong>DOI:<\/strong> <a href=\"https:\/\/doi.org\/10.4103\/tcmj.tcmj_59_24\">10.4103\/tcmj.tcmj_59_24<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Impact Factor:<\/strong> 2.4 \u00a0 | \u00a0\u00a0<strong>Category Rank:<\/strong>\u00a094\/336, Medicine, General &amp; Internal \u00a0 | \u00a0\u00a0<strong>Top 28%<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><small>* Corresponding author; \u2020 equal contribution, as indicated in the source publication records.<\/small><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selected peer-reviewed publications by members of the Center for Herbal Medicine and Natural Products Research. Entries are arranged in reverse chronological order. Journal metrics use the 2025 Journal Citation Reports &#8230;<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-23","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/hmnprc.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/23","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hmnprc.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hmnprc.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hmnprc.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/hmnprc.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=23"}],"version-history":[{"count":8,"href":"https:\/\/hmnprc.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/23\/revisions"}],"predecessor-version":[{"id":163,"href":"https:\/\/hmnprc.tcu.edu.tw\/index.php?rest_route=\/wp\/v2\/pages\/23\/revisions\/163"}],"wp:attachment":[{"href":"https:\/\/hmnprc.tcu.edu.tw\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=23"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}